57 research outputs found

    Conference report: 18th conference on computer-assisted qualitative data analysis (CAQD) 2016: MAXQDA user conference

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    During the first week of March 2016, 120 researchers from 12 different countries, including Syria, Japan, the USA and Turkey, met in Berlin (Germany) to learn more about their computer-assisted qualitative data analysis skills. The 18th Conference on Computer-Assisted Qualitative Data Analysis (CAQD) offered several workshops, a research methods poster session, and the opportunity to share and discuss best practice between attendees, trainers and speakers (informally and through the user forum). The conference also hosted three seminal keynote speakers in two presentations: John CRESWELL, and Udo KUCKARTZ and Stefan RÄDIKER, who shared, respectively, the state of the art of mixed methods and the ways that software can support these approaches

    Combining diverse data sources for CEDSS, an agent-based model of domestic energy demand

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    CEDSS (Community Energy Demand Social Simulator) is an empirical agent-based model designed and built as part of a multi-method social science project investigating the determinants of domestic energy demand. Ideally, empirical modellers, within and beyond social simulation, would prefer to work from an integrated dataset, gatheredfor the purposes of developing the model. In practice, many have to work with less than ideal data, often including processed data from multiple sources external to the project. Moreover, what data will be required may not be clear at the start of the project. This paper describes the approach to dealing with these factors taken in developing CEDSS, and presents the completed model together with an outline of the calibration and validation procedure used. The discussion section draws together the most distinctive features of empirical data collection, processing and use for and in CEDSS, and argues that the approach taken is sufficiently robust to underpin the model’s purpose – to generate scenarios of domestic energy demand to 2049

    How to recreate a Viking funeral – minus the human sacrifice

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    First paragraph: When most people think of Vikings, they think of the usual stuff: longships, raiding, fighting, loot, burial and paganism. Scholars are increasingly aware that the reality was more complicated, but no doubt the popular associations will remain – and are reinforced by the likes of last year’s Viking exhibition at the British Museum in London. Access this article at The Conversation webpage: https://theconversation.com/how-to-recreate-a-viking-funeral-minus-the-human-sacrifice-3909

    Digital Innovation Through Partnership Between Nature Conservation Organisations and Academia : A Qualitative Impact Assessment

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    We would like to thank all interviewees for sharing their experiences of working with academics, and the guest editor and three anonymous reviewers for valuable comments on earlier versions of the work. The research in this paper is supported by the RCUK dot.rural Digital economy Research Hub, University of Aberdeen (Grant reference: EP/G066051/1).Peer reviewedPublisher PD

    Responses to representations of the built environment: the influence of emotion, attention and perspective-taking.

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    The main aim of this thesis is to investigate how environmental preference for the built environment, either in-situ or based on visual representations (e.g. visualisations of final architectural design), may be affected by three distinct variables. One of them is emotion, operationalised as the mood people are in at the time of the evaluation and the way people feel with regards to the environment. A second variable considers the participants' attention and how they may be influenced by task instructions. The third variable, intrinsically related to the second one, is how environmental preference may be influenced depending on the perspective taken at the time of the evaluation. The main research questions in this thesis are: a) How does emotion influence environmental preference' b) What is the impact of perspective-taking on environmental preference' c) What are the benefits of using emotional reactions to the environment as predictors of preference? These main research questions are addressed using both quantitative and qualitative methods, mainly quantitative, underpinned by a pragmatic approach. The unit of analysis in this thesis is the person who evaluates or judges an environment or a representation of it. Five studies are presented in this thesis. Study 1 (n=10) reports the results from interviews with practising architects in the city of Aberdeen. These results show that when designing architects take two distinct perspectives: a prescriptive inferential perspective and a self, referential perspective. These interviews are used to set the context within which this thesis operates: the presentation of design to people with no expertise in architecture and built environment disciplines. The remaining four studies directly address this thesis' main research questions. In Study 2 (n=133), Study 3 (n=146) and Study 5 (n=64) the effects of perspective-taking on different dependent variables are experimentally tested. The dependent variables are: perceived restorativeness (Study 2), environmental preference as measured via informational variables (Study 3), and the emotional reactions people have to representations of the environment (Study 5). Results of these studies show that perspective-taking carries an interpersonal perception bias whereby taking a perspective other than the self results in different environmental evaluation outcomes, but that this process can also be affected by formal training. The influences of emotion on environmental preference are directly explored in Studies 4 (n=32) and 5 (n=64). The results show that mood can have an influence on environmental preference by influencing the emotional reactions people have to the environment, but that these influences vary over time. Overall the thesis shows that perspective-taking and emotion have a range of influences on environmental preference in a built environment context, that these are important at the point at which architecture and built environment professionals design environments, and that timing of environmental evaluations in longitudinal assessments can make the difference between positive and less positive evaluations. This thesis' results are discussed in light of existing knowledge and some recommendations are made for future research and practitioners in architecture and built environment disciplines

    Capturing and utilising information on the impact of research

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    This 7-minute presentation by Carlos Galan-Diaz and Rose-Marie Barbeau, both of the University of Glasgow, was given at RepoFringe 2016 on Monday 1st August 2016 as part of the 24x7 session on 'Making a Difference with Data'. The presentation defines and describes what research impact is and the types of evidence which may be collected to demonstrate impact. It also describes how eprints is used at the University of Glasgow to record impact

    Dynamic Edematous Response of the Human Heart to Myocardial Infarction Implications for Assessing Myocardial Area at Risk and Salvage

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    BACKGROUND: Clinical protocols aimed to characterize the post-myocardial infarction (MI) heart by cardiac magnetic resonance (CMR) need to be standardized to take account of dynamic biological phenomena evolving early after the index ischemic event. Here, we evaluated the time course of edema reaction in patients with ST-segment-elevation MI by CMR and assessed its implications for myocardium-at-risk (MaR) quantification both in patients and in a large-animal model. METHODS: A total of 16 patients with anterior ST-segment-elevation MI successfully treated by primary angioplasty and 16 matched controls were prospectively recruited. In total, 94 clinical CMR examinations were performed: patients with ST-segment-elevation MI were serially scanned (within the first 3 hours after reperfusion and at 1, 4, 7, and 40 days), and controls were scanned only once. T2 relaxation time in the myocardium (T2 mapping) and the extent of edema on T2-weighted short-tau triple inversion-recovery (ie, CMR-MaR) were evaluated at all time points. In the experimental study, 20 pigs underwent 40-minute ischemia/reperfusion followed by serial CMR examinations at 120 minutes and 1, 4, and 7 days after reperfusion. Reference MaR was assessed by contrast-multidetector computed tomography during the index coronary occlusion. Generalized linear mixed models were used to take account of repeated measurements. RESULTS: In humans, T2 relaxation time in the ischemic myocardium declines significantly from early after reperfusion to 24 hours, and then increases up to day 4, reaching a plateau from which it decreases from day 7. Consequently, edema extent measured by T2-weighted short-tau triple inversion-recovery (CMR-MaR) varied with the timing of the CMR examination. These findings were confirmed in the experimental model by showing that only CMR-MaR values for day 4 and day 7 postreperfusion, coinciding with the deferred edema wave, were similar to values measured by reference contrast-multidetector computed tomography. CONCLUSIONS: Post-MI edema in patients follows a bimodal pattern that affects CMR estimates of MaR. Dynamic changes in post-ST-segment-elevation MI edema highlight the need for standardization of CMR timing to retrospectively delineate MaR and quantify myocardial salvage. According to the present clinical and experimental data, a time window between days 4 and 7 post-MI seems a good compromise solution for standardization. Further studies are needed to study the effect of other factors on these variables.This study was partially supported by a competitive grant from the Spanish Society of Cardiology (Proyectos de Investigacion Traslacional en Cardiologia de la Sociedad Espanola de Cardiologia 2015, for the project Caracterizacion tiSUlar miocaRdica con resonancia magnetica en pacientes tras inFarto agudo de mioCardio con elevacioN de ST sometidos a angloplastia Coronaria primaria. Estudio SURF-CNIC), by a competitive grant from the Carlos III Institute of Health-Fondo de Investigacion Sanitaria- and the European Regional Development Fund (ERDF/FEDER) (PI10/02268 and PI13/01979), the Spanish Ministry of economy, industry, and competitiveness (MEIC) and ERDF/FEDER SAF2013-49663-EXP. Dr Fernandez-Jimenez holds a FICNIC fellowship from the Fundacio Jesus Serra, the Fundacion Interhospitalaria de Investigacion Cardiovascular, and the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), and Dr Aguero is a FP7-PEOPLE-2013-ITN-Cardionext fellow. This study forms part of a Master Research Agreement between the CNIC and Philips Healthcare, and is part of a bilateral research program between Hospital de Salamanca Cardiology Department and the CNIC. This research program is part of an institutional agreement between FIIS-Fundacion Jimenez Diaz and CNIC. The CNIC is supported by the MEIC and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (MEIC award SEV-2015-0505).S

    Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort

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    Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, the residual risk observed in prediction models is still high. Therefore, new risk factors need to be identified in order to better predict the risk of CKD in the population. Here, we analyzed the genetic association of 79 SNPs of proteins associated with mineral metabolism disturbances with CKD in a cohort that includes 2, 445 CKD cases and 559 controls. Genotyping was performed with matrix assisted laser desorption ionizationtime of flight mass spectrometry. We used logistic regression models considering different genetic inheritance models to assess the association of the SNPs with the prevalence of CKD, adjusting for known risk factors. Eight SNPs (rs1126616, rs35068180, rs2238135, rs1800247, rs385564, rs4236, rs2248359, and rs1564858) were associated with CKD even after adjusting by sex, age and race. A model containing five of these SNPs (rs1126616, rs35068180, rs1800247, rs4236, and rs2248359), diabetes and hypertension showed better performance than models considering only clinical risk factors, significantly increasing the area under the curve of the model without polymorphisms. Furthermore, one of the SNPs (the rs2248359) showed an interaction with hypertension, being the risk genotype affecting only hypertensive patients. We conclude that 5 SNPs related to proteins implicated in mineral metabolism disturbances (Osteopontin, osteocalcin, matrix gla protein, matrix metalloprotease 3 and 24 hydroxylase) are associated to an increased risk of suffering CKD

    Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

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    Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
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